Abstract
Résumé
Keywords
Mots clés
Introduction
Grady D. Diabetes treatment disappoints in new study. The New York Times: Sep. 27, 2006. http://www.nytimes.com/2006/09/27/health/27cnd-diabetes.html. Accessed February 6, 2012.
Historical Perspective
Previous Assessments of Risks of Islet Transplantation
Procedural risks
Risks of immunosuppression
Unusual complications
Renal outcomes
Adverse drug effects

Reappraisal of the Benefits of Islet Transplantation
2009 Scientific Summary of the Collaborative Islet Transplant Registry (CITR). Rockville, MD: 2009. http://www.citregistry.org/. Accessed February 6, 2012.
Primary goals for islet transplantation | Primary indications for islet transplantation | Contraindications to islet transplant |
---|---|---|
|
|
|
Recent Progress and Refinements in Islet Transplantation


Positive impact on complications
Improving transplant outcomes
Edmonton’s Current Status

Age (years) | 46.5 (24-69) |
Diabetes duration (years) | 29.4 ± 11.3 |
Male/female | 62/76 |
Weight (kg) | 71.1 ± 11.8 |
BMI (kg/m2) | 24.8 ± 3.1 |
Insulin requirements (u/kg/day) | 0.6 ± 0.17 |
Full function | Partial function | Graft loss | |
---|---|---|---|
N (%) | 48 (35%) | 61 (44%) | 29 (21%) |
Male/female | 26/22 | 29/32 | 7/22 |
Current A1C (%) | 6.1 ± 0.4 | 7.0 ± 1.1 | 8.3 ± 1.0 |
Achieved insulin independence | 48 (100%) | 41 (67%) | 16 (55%) |
Duration of insulin independence (months) | 34.6 (1-143) | 11.0 (0-75) | 1.8 (0-41) |
Duration of c-peptide positivity (months) | 55.3 (3-145) | 70.4 (2-147) | 34.8 (0-116) |
Number of donors | 2.4 ± 0.9 | 2.4 ± 0.9 | 2.2 ± 0.8 |
Islets transplanted (i.e. kg) | 13057 ± 3763 | 12827 ± 4701 | 12977 ± 4698 |
Conclusion
Author Disclosures
References
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