Type 1 diabetes impairs muscle growth and absolute force production in developing skeletal muscle

      Background: Type 1 diabetes mellitus (T1DM) is often diagnosed in childhood, a time of growth and development. Studies on the effect of T1DM on growing skeletal muscle are limited and those that have been performed have largely used the streptozotocin model. Unfortunately, streptozotocin itself directly causes myopathy independent of hypoinsulinemia/hyperglycemia.
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