Abstract
Objective
To describe the characteristics of type 2 diabetes mellitus in youth (<18 years) at
diagnosis from 2006 to 2011 referred to the Diabetes Education Resource for Children
and Adolescents in Winnipeg, Manitoba.
Methods
A retrospective review of the clinical presentation of youth with type 2 diabetes
during a 5-year period using a clinical database. Descriptive statistics were used
to analyze the data. Analysis of variance was used to look for differences in the
means between the groups categorized by year of diagnosis.
Results
The majority of youth (198/227; 87%) had First Nation heritage. The average age at
diagnosis was 13.2 ± 2.3 years, with 9.7% <10 years at diagnosis. A 2:1 female predominance
was found. Eighty percent were obese and 4.4% presented in diabetic ketoacidosis.
Seventy-five percent live in rural or remote communities. In Manitoba, the annual
incidence of type 2 diabetes in youth increased from 9.03 to 20.55/100 000 youth/year
over the study period.
Conclusion
The incidence of type 2 diabetes in youth in Manitoba is increasing. A significant
proportion of youth were diagnosed before 10 years of age and were not obese at diagnosis
making the importance of community and healthcare provider awareness of the varying
phenotype of type 2 diabetes in youth paramount to inform early detection, treatment
and prevention strategies.
Résumé
Objectif
Décrire les caractéristiques du diabète sucré de type 2 chez les jeunes âgés de <
18 ans au diagnostic de 2006 à 2011 et dirigés au Diabetes Education Resource for
Children and Adolescents à Winnipeg au Manitoba.
Méthodes
Une revue rétrospective du tableau clinique de jeunes ayant le diabète de type 2 durant
une période de 5 ans a été effectuée en utilisant une base de données clinique. Les
statistiques descriptives ont été utilisées pour analyser les données. L’analyse de
variance a été utilisée pour relever les différences de moyennes entre les groupes
catégorisés par année de diagnostic.
Résultats
La majorité des jeunes (198/227; 87 %) étaient d’ascendance liée aux Premières Nations.
La moyenne d’âge au diagnostic était 13,2 ± 2,3 ans, dont 9,7 % < 10 ans au diagnostic.
Une prédominance féminine de 2:1 était observée. Quatre-vingts pour cent (80 %) étaient
obèses et 4,4 % souffraient de kétoacidose diabétique. Soixante-quinze pour cent (75
%) vivaient dans des communautés rurales ou éloignées. Au Manitoba, l’incidence annuelle
du diabète de type 2 chez les jeunes a augmenté de 9,03 à 20,55/100 000 jeunes par
année durant la période étudiée.
Conclusion
L’incidence du diabète de type 2 chez les jeunes du Manitoba augmente. Une proportion
significative de jeunes avait reçu un diagnostic avant l’âge de 10 ans et n’était
pas obèse au diagnostic, ce qui confirme que sensibiliser la communauté et le fournisseur
en soins de santé sur la diversité phénotypique du diabète de type 2 chez les jeunes
est essentiel pour informer précocement des stratégies de détection, de traitement
et de prévention.
Keywords
Mots clés
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Article info
Publication history
Accepted:
April 27,
2012
Received in revised form:
April 20,
2012
Received:
January 27,
2012
Identification
Copyright
© 2012 Canadian Diabetes Association. Published by Elsevier Inc. All rights reserved.
