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Eating Behaviours and Prevalence of Gastroesophageal Reflux Disease in Japanese Adult Patients With Type 2 Diabetes Mellitus: The Dogo Study

Published:October 19, 2017DOI:https://doi.org/10.1016/j.jcjd.2017.07.007

      Abstract

      Objectives

      In the general population, late-night dinner is positively associated with gastroesophageal reflux disease (GERD). No evidence exists regarding the relationship between eating behaviours and GERD in patients with type 2 diabetes mellitus, though the prevalence of GERD in patients with type 2 diabetes is higher than in those without diabetes. We conducted this study to investigate the association between eating behaviours and GERD in Japanese patients with type 2 diabetes.

      Methods

      The study's subjects were 817 Japanese patients with type 2 diabetes. GERD was defined as being present when a subject had a Quality of Life and Utility Evaluation Survey Technology (QUEST) score of 4 or higher. The assessment of eating behaviour was performed by self-administered questionnaire. Subjects were considered positive for late-night dinner if they answered yes to the question “Do you eat dinner within 2 hours before bedtime at least 3 times per week?

      Results

      The prevalence values of GERD, skipping breakfast, bedtime snacking, late-night dinner and fast eating were 32.0%, 13.7%, 27.1%, 28.8%, and 44.4%, respectively. Late-night dinner was independently positively associated with GERD in patients with type 2 diabetes; the adjusted odds ratio was 1.46 (95% CI 1.03 to 2.05). No relationships were found between skipping breakfast, bedtime snacking or fast eating and GERD.

      Conclusions

      Late-night dinner may be positively associated with GERD in Japanese patients with type 2 diabetes.

      Résumé

      Objectifs

      Dans la population générale, le souper tardif est associé de manière positive au reflux gastro-œsophagien (RGO) pathologique. Aucune donnée probante n'existe au sujet de la relation entre les comportements alimentaires et le RGO chez les patients atteints du diabète sucré de type 2, pourtant la prévalence du RGO chez les patients atteints du diabète de type 2 est plus élevée que chez les patientsnon diabétiques. Nous avons mené la présente étude pour examiner l'association entre les comportements alimentaires et le RGO chez des patients japonais atteints du diabète de type 2.

      Méthodes

      Les 817 sujets de l'étude étaient des patients japonais atteints du diabète de type 2. Le RGO était défini comme étant présent lorsqu'un sujet obtenait un score de 4 ou plus au Quality of Life and Utility Evaluation Survey Technology (QUEST). Le questionnaireauto-administré a permis d'évaluer les comportements alimentaires. On considérait les sujets comme étant positifs en ce qui concerne le souper tardif s'ils répondaient par oui à la question « Prenez-vous votre souper 2 heures avant d'aller au lit 3 fois par semaine? ».

      Résultats

      Les valeurs de la prévalence du RGO, du déjeuner escamoté, de la collation au coucher, du souper tardif et de l'alimentation rapide étaient respectivement de 32.0%, 13.7%, 27.1%, 28.8%, et 44.4%. Le souper tardif était indépendamment associé de manière positive au RGO chez les patients atteints du diabète de type 2; le ratio d'incidence approché était de 1,46 (IC à 95 %, de 1,03 à 2,05). Aucune relation n'était observée entre le déjeuner escamoté, la collation au coucher ou l'alimentation rapide, et le RGO.

      Conclusions

      Le souper tardif peut être associé de manière positive au RGO chez les patients japonais atteints du diabète de type 2.

      Keywords

      Mots clés

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