Abstract
Objectives
In the general population, late-night dinner is positively associated with gastroesophageal
reflux disease (GERD). No evidence exists regarding the relationship between eating
behaviours and GERD in patients with type 2 diabetes mellitus, though the prevalence
of GERD in patients with type 2 diabetes is higher than in those without diabetes.
We conducted this study to investigate the association between eating behaviours and
GERD in Japanese patients with type 2 diabetes.
Methods
The study's subjects were 817 Japanese patients with type 2 diabetes. GERD was defined
as being present when a subject had a Quality of Life and Utility Evaluation Survey
Technology (QUEST) score of 4 or higher. The assessment of eating behaviour was performed
by self-administered questionnaire. Subjects were considered positive for late-night
dinner if they answered yes to the question “Do you eat dinner within 2 hours before
bedtime at least 3 times per week?
Results
The prevalence values of GERD, skipping breakfast, bedtime snacking, late-night dinner
and fast eating were 32.0%, 13.7%, 27.1%, 28.8%, and 44.4%, respectively. Late-night
dinner was independently positively associated with GERD in patients with type 2 diabetes;
the adjusted odds ratio was 1.46 (95% CI 1.03 to 2.05). No relationships were found
between skipping breakfast, bedtime snacking or fast eating and GERD.
Conclusions
Late-night dinner may be positively associated with GERD in Japanese patients with
type 2 diabetes.
Résumé
Objectifs
Dans la population générale, le souper tardif est associé de manière positive au reflux
gastro-œsophagien (RGO) pathologique. Aucune donnée probante n'existe au sujet de
la relation entre les comportements alimentaires et le RGO chez les patients atteints
du diabète sucré de type 2, pourtant la prévalence du RGO chez les patients atteints
du diabète de type 2 est plus élevée que chez les patientsnon diabétiques. Nous avons
mené la présente étude pour examiner l'association entre les comportements alimentaires
et le RGO chez des patients japonais atteints du diabète de type 2.
Méthodes
Les 817 sujets de l'étude étaient des patients japonais atteints du diabète de type
2. Le RGO était défini comme étant présent lorsqu'un sujet obtenait un score de 4
ou plus au Quality of Life and Utility Evaluation Survey Technology (QUEST). Le questionnaireauto-administré
a permis d'évaluer les comportements alimentaires. On considérait les sujets comme
étant positifs en ce qui concerne le souper tardif s'ils répondaient par oui à la
question « Prenez-vous votre souper 2 heures avant d'aller au lit 3 fois par semaine?
».
Résultats
Les valeurs de la prévalence du RGO, du déjeuner escamoté, de la collation au coucher,
du souper tardif et de l'alimentation rapide étaient respectivement de 32.0%, 13.7%,
27.1%, 28.8%, et 44.4%. Le souper tardif était indépendamment associé de manière positive
au RGO chez les patients atteints du diabète de type 2; le ratio d'incidence approché
était de 1,46 (IC à 95 %, de 1,03 à 2,05). Aucune relation n'était observée entre
le déjeuner escamoté, la collation au coucher ou l'alimentation rapide, et le RGO.
Conclusions
Le souper tardif peut être associé de manière positive au RGO chez les patients japonais
atteints du diabète de type 2.
Keywords
Mots clés
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References
- The impact of nocturnal symptoms associated with gastoesophageal reflux disease on health-related quality of life.Arch Intern Med. 2001; 161: 45-52
- Impact of chronic gastrointestinal symptoms in diabetes mellitus on health-related quality of life.Am J Gastroenterol. 2001; 96: 71-76
- Association between dinner-to-bedtime and gastro-esophageal reflux disease.Am J Gastroenterol. 2005; 100: 2633-2636
- Patterns of diet-related practices and prevalence of gastro-esophageal reflux disease.Neurogastroenterol Motil. 2013; 25: 831-838
- Adherence to a predominantly Mediterranean diet decreases the risk of gastroesophageal reflux disease: A cross-sectional study in a South Eastern European population.Dis Esophagus. 2016; 29: 794-800
- Recurrence of gastroesophageal reflux disease correlated with a short dinner-to-bedtime interval.J Gastroenterol Hepatol. 2014; 29: 730-735
- Lifestyle factors affecting gastroesophageal reflux disease symptoms: A cross-sectional study of 19 864 healthy adults using FSSG scores.BMC Med. 2012; 10: 45
- Gastroesophageal reflux disease prevalence in the city of Sivas.Turk J Gastroenterol. 2013; 24: 303-310
- Association of hyperglycemia in a general Japanese population with late-night-dinner eating alone, but not breakfast skipping alone.J Diabetes Metab Disord. 2015; 14: 16
- Potential association between breakfast skipping and concomitant late-night-dinner eating with metabolic syndrome and proteinuria in the Japanese population.Scientifica. 2014; 201: 253581
- Association between diabetes mellitus and gastroesophageal reflux disease: A meta-analysis.World J Gastroenterol. 2015; 21: 3085-3092
- The relationship between type 2 diabetes mellitus and failure of proton pump inhibitor treatment in gastroesophageal reflux disease.J Clin Gastroenterol. 2012; 46: 662-668
- A new classification of diabetic nephropathy 2014: A report from Joint Committee on Diabetic Nephropathy.J Diabetes Investig. 2015; 6: 242-246
- Rationale and usefulness of newly devised abbreviated diagnostic criteria and staging for diabetic polyneuropathy.Diabetes Res Clin Pract. 2007; 77: S178-S183
- (in Japanese)
- The usefulness of a structured questionnaire in the assessment of symptomatic gastroesophageal reflux disease.Scand J Gastroenterol. 1998; 33: 1023-1029
- Lifestyle factors associated with gastroesophageal reflux disease in the Japanese population.J Gastroenterol. 2013; 48: 340-349
- The effect of the speed of eating on acid reflux and symptoms of patients with gastroesophageal reflux disease.Turk J Gastroenterol. 2013; 24: 379-381
- Early dinner reduces nocturnal gastric acidity.Gut. 1989; 30: 1063-1067
- The timing of the evening meal affects the pattern of 24-hour intragastric acidity.Aliment Pharmacol Ther. 1990; 4: 547-553
- Mechanisms of gastroesophageal reflux in patients with reflux esophagitis.N Engl J Med. 1982; 307: 1547-1552
- Nocturnal reflux episodes following the administration of a standardized meal: Does timing matter?.Am J Gastroenterol. 2007; 102: 2128-2134
- Is the questionnaire for the assessment of gastroesophageal reflux useful for diabetic patients?.Scand J Gastroenterol. 2005; 40: 1017-1020
- Symptoms of gastroesophageal reflux in diabetes patients.Diabetes Res Clin Pract. 2008; 79: e6-e7
- Comparative study of 2 different questionnaires in Japanese patients: The quality of life and utility evaluation survey technology questionnaire (QUEST) versus the frequency scale for the symptoms of gastroesophageal reflux disease questionnaire (FSSG).J Neurogastroenterol Motil. 2013; 19: 54-60
- Comparison of endoscopic findings with symptom assessment systems (FSSG and QUEST) for gastroesophageal reflux disease in Japanese centres.J Gastroenterol Hepatol. 2009; 24: 633-638
- Epidemiology and clinical characteristics of GERD in the Japanese population.J Gastroenterol. 2009; 44: 518-534
Article Info
Publication History
Published online: October 19, 2017
Accepted:
July 31,
2017
Received in revised form:
June 25,
2017
Received:
March 19,
2017
Footnotes
All authors made equal contributions to this work and share first authorship.
The Canadian Diabetes Association is the registered owner of the name Diabetes Canada.
Identification
Copyright
© 2017 Canadian Diabetes Association.
