Introduction: The Bethesda System for Reporting Thyroid Cytopathology (TBSRTC) characterizes thyroid
fine-needle aspiration cytology (FNAC) into 1 of 6 diagnostic categories, each with
a corresponding rate of malignancy (ROM) that may be influenced by factors such as
the nodule risk stratification pathway, technical and cytopathology experience, statistical
method used to calculate malignancy rates and duration of follow up. The aim of this
study was to establish the local ROM for TBSRTC categories in order to guide clinical
decision making in Southern Alberta.
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