Original Research| Volume 45, ISSUE 5, P428-435, July 2021

Comparison of Clinical and Social Characteristics of Canadian Youth Living With Type 1 and Type 2 Diabetes

Published:January 22, 2021DOI:



      Our aim in this study was to describe the clinical and social characteristics of 2 Canadian cohorts of adolescents with diabetes.


      Participants from the Improving renal Complications in Adolescents with type 2 diabetes through REsearch (iCARE) study (n=322) and the Early Determinants of Cardio-Renal Disease in Youth With Type 1 Diabetes (n=199) study were compared.


      Adolescents were 10 to 18 years of age (mean ± standard deviation: 14.8±2.4 years). The T2DM cohort had a shorter duration of diabetes. Both groups had glycated hemoglobin levels above target. The type 2 diabetes (T2D) cohort was comprised of predominantly Indigenous youth. The type 1 diabetes (T1D) cohort was 58.3% European/Caucasian, with a high proportion (41.7%) of visible minority groups (Afro-Caribbean, Asian/Pacific Islander, Hispanic). The prevalence of obesity, hypertension, left ventricular hypertrophy, albuminuria and hyperfiltration was higher in the T2D cohort. The T1D cohort was more socially and economically advantaged in all 4 dimensions of health inequality.


      There are significant differences in clinical and social characteristics of adolescents with T2D and T1D in Canada. Both have inadequate glycemic control with evidence of onset and progression of diabetes-related complications.



      L’objectif de notre étude était de décrire les caractéristiques cliniques et sociales de 2 cohortes canadiennes d’adolescents diabétiques.


      Nous avons comparé les participants à l’étude Improving renal Complications in Adolescents with type 2 diabetes through REsearch (iCARE) (n = 322) et les participants à l’étude Early Determinants of Cardio-Renal Disease in Youth With Type 1 Diabetes (n = 199).


      Les adolescents avaient de 10 à 18 ans (moyenne ± écart type : 14,8 ± 2,4 ans). La cohorte atteinte du diabète de type 2 (DT2) souffrait du diabète depuis moins longtemps. Les 2 groupes avaient des concentrations d’hémoglobine glyquée au-dessus des valeurs visées. La cohorte atteinte du DST2 était majoritairement composée de personnes autochtones. La cohorte atteinte du diabète de type 1 (DT1) était composée de 58,3 % d’Européens blancs, dont une forte proportion (41,7 %) de groupes des minorités visibles (Afro-Antillais, Asiatiques/insulaires du Pacifique, Hispaniques). La prévalence de l’obésité, de l’hypertension, de l’hypertrophie ventriculaire gauche, de l’albuminurie et de l’hyperfiltration était plus élevée dans la cohorte atteinte du DT2. La cohorte atteinte du DT1 était plus socialement et économiquement favorisée dans les 4 dimensions des inégalités en santé.


      Il existe des différences significatives entre les caractéristiques cliniques et sociales des adolescents atteints du DT2 et celles des adolescents atteints du DT1 au Canada. Les 2 cohortes ont une mauvaise régulation de la glycémie qui se manifeste par l’apparition et la progression des complications liées au diabète.


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