Abstract
Objectives
Our aim in this study was to describe the clinical and social characteristics of 2
Canadian cohorts of adolescents with diabetes.
Methods
Participants from the Improving renal Complications in Adolescents with type 2 diabetes
through REsearch (iCARE) study (n=322) and the Early Determinants of Cardio-Renal
Disease in Youth With Type 1 Diabetes (n=199) study were compared.
Results
Adolescents were 10 to 18 years of age (mean ± standard deviation: 14.8±2.4 years).
The T2DM cohort had a shorter duration of diabetes. Both groups had glycated hemoglobin
levels above target. The type 2 diabetes (T2D) cohort was comprised of predominantly
Indigenous youth. The type 1 diabetes (T1D) cohort was 58.3% European/Caucasian, with
a high proportion (41.7%) of visible minority groups (Afro-Caribbean, Asian/Pacific
Islander, Hispanic). The prevalence of obesity, hypertension, left ventricular hypertrophy,
albuminuria and hyperfiltration was higher in the T2D cohort. The T1D cohort was more
socially and economically advantaged in all 4 dimensions of health inequality.
Conclusions
There are significant differences in clinical and social characteristics of adolescents
with T2D and T1D in Canada. Both have inadequate glycemic control with evidence of
onset and progression of diabetes-related complications.
Résumé
Objectifs
L’objectif de notre étude était de décrire les caractéristiques cliniques et sociales
de 2 cohortes canadiennes d’adolescents diabétiques.
Méthodes
Nous avons comparé les participants à l’étude Improving renal Complications in Adolescents
with type 2 diabetes through REsearch (iCARE) (n = 322) et les participants à l’étude
Early Determinants of Cardio-Renal Disease in Youth With Type 1 Diabetes (n = 199).
Résultats
Les adolescents avaient de 10 à 18 ans (moyenne ± écart type : 14,8 ± 2,4 ans). La
cohorte atteinte du diabète de type 2 (DT2) souffrait du diabète depuis moins longtemps.
Les 2 groupes avaient des concentrations d’hémoglobine glyquée au-dessus des valeurs
visées. La cohorte atteinte du DST2 était majoritairement composée de personnes autochtones.
La cohorte atteinte du diabète de type 1 (DT1) était composée de 58,3 % d’Européens
blancs, dont une forte proportion (41,7 %) de groupes des minorités visibles (Afro-Antillais,
Asiatiques/insulaires du Pacifique, Hispaniques). La prévalence de l’obésité, de l’hypertension,
de l’hypertrophie ventriculaire gauche, de l’albuminurie et de l’hyperfiltration était
plus élevée dans la cohorte atteinte du DT2. La cohorte atteinte du DT1 était plus
socialement et économiquement favorisée dans les 4 dimensions des inégalités en santé.
Conclusions
Il existe des différences significatives entre les caractéristiques cliniques et sociales
des adolescents atteints du DT2 et celles des adolescents atteints du DT1 au Canada.
Les 2 cohortes ont une mauvaise régulation de la glycémie qui se manifeste par l’apparition
et la progression des complications liées au diabète.
Keywords
Mots clés
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Article info
Publication history
Published online: January 22, 2021
Accepted:
January 16,
2021
Received in revised form:
January 11,
2021
Received:
October 30,
2020
Identification
Copyright
© 2021 Canadian Diabetes Association.
